Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 5/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797339 | 0.90 | GPR35 (0.53) | GSK3BGPR35TTRMEN1KMT2A | |
| SCHEMBL7247935 | 0.85 | TTR (0.56) | GSK3BGPR35TTRMEN1KMT2A | |
| SCHEMBL10880580 | 0.83 | TTR (0.57) | GPR35TTRERN1MEN1KMT2A | |
| SCHEMBL9706244 | 0.81 | TTR (0.62) | GPR35TTRERN1 | |
| SCHEMBL1191123 | 0.80 | TTR (0.58) | GSK3BTTRESR1 | |
| SCHEMBL11802641 | 0.80 | GPR35 (0.47) | GPR35TTRERN1CA12CA1 | |
| SCHEMBL11796876 | 0.80 | GPR35 (0.46) | GPR35TTRERN1MEN1KMT2A | |
| SCHEMBL7365455 | 0.79 | TTR (0.57) | GSK3BTTR | |
| SCHEMBL14161366 | 0.79 | GSK3B (0.57) | GSK3BMEN1KMT2A | |
| SCHEMBL6742322 | 0.79 | GSK3B (0.57) | GSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933472-A | Substituted alkylaryl ketones and methods of use as herbicides | BUCKMAN LABORATORIES, INC. (US) | 1976-01-20 | — | — | US | disclosed |