Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71079 | 0.70 | NPC1 (0.41) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL3133033 | 0.70 | NPC1 (0.45) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL1713917 | 0.69 | NPC1 (0.41) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL1164959 | 0.69 | RAB9A (0.44) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL11055771 | 0.69 | NPC1 (0.44) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL4648988 | 0.68 | NPC1 (0.40) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL354611 | 0.67 | NPC1 (0.41) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL3735368 | 0.67 | RAB9A (0.45) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL11799791 | 0.67 | NPC1 (0.36) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL6238756 | 0.66 | BTK (0.41) | NPC1RAB9AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3973959-A | Electrophotographic recording material and process for its manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |