Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795536 | 0.81 | FFAR4 (0.67) | FFAR4FFAR1ALDH1A1 | |
| SCHEMBL11793908 | 0.81 | FFAR4 (0.67) | FFAR4FFAR1ALDH1A1 | |
| SCHEMBL11795163 | 0.81 | KDM4C (0.48) | FFAR4FFAR1EPHX2GSTK1 | |
| SCHEMBL11786566 | 0.80 | MAPT (0.50) | MAPTABCC4FFAR4FFAR1EPHX2 | |
| SCHEMBL11792939 | 0.80 | MAPT (0.50) | MAPTABCC4FFAR4FFAR1EPHX2 | |
| SCHEMBL11792462 | 0.80 | FFAR4 (0.45) | FFAR4FFAR1GSTK1 | |
| SCHEMBL11604163 | 0.79 | ABCC4 (0.49) | MAPTABCC4FFAR4FFAR1EPHX2 | |
| SCHEMBL18955685 | 0.78 | MAPT (0.74) | MAPTABCC4FFAR4FFAR1USP2 | |
| SCHEMBL4412671 | 0.78 | MAPT (0.74) | MAPTABCC4FFAR4FFAR1USP2 | |
| SCHEMBL11793752 | 0.78 | FFAR4 (0.43) | FFAR4FFAR1GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989749-A | RENAL VASODILATORS, ANTITHROMBUS | MERCK & CO., INC. (US) | 1976-11-02 | — | — | US | disclosed |