Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.48 |
| ▸ | KDM4A | O75164 | 3/20 | 0.48 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11793908 | 0.86 | FFAR4 (0.67) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11795536 | 0.86 | FFAR4 (0.67) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11792462 | 0.85 | FFAR4 (0.45) | KDM4CKDM4APHF8KDM2AFFAR4 | |
| SCHEMBL11799699 | 0.81 | MAPT (0.49) | FFAR4FFAR1EPHX2GSTK1 | |
| SCHEMBL11793752 | 0.80 | FFAR4 (0.43) | KDM4CKDM4APHF8KDM2AFFAR4 | |
| SCHEMBL11786835 | 0.80 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AFFAR4 | |
| SCHEMBL11601867 | 0.79 | KDM4C (0.49) | KDM4CKDM4APHF8KDM2AFFAR4 | |
| SCHEMBL11791379 | 0.77 | KDM4C (0.47) | KDM4CKDM4APHF8KDM2AFFAR4 | |
| SCHEMBL11790456 | 0.75 | ACE2 (0.50) | FFAR4FFAR1 | |
| Water SCHEMBL28053000 | 0.73 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989749-A | RENAL VASODILATORS, ANTITHROMBUS | MERCK & CO., INC. (US) | 1976-11-02 | — | — | US | disclosed |