Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15397710 | 0.94 | TTR (0.56) | TTRNPC1RAB9APTPN1MAPT | |
| SCHEMBL10170968 | 0.89 | TTR (0.49) | TTRNPC1RAB9AAKR1B1KDM4E | |
| SCHEMBL12683149 | 0.86 | TTR (0.44) | TTRNPC1RAB9APTPN1MAPT | |
| SCHEMBL3875921 | 0.85 | TTR (0.54) | TTRNPC1RAB9APTPN1MAPT | |
| SCHEMBL15842775 | 0.81 | PTPN1 (0.41) | TTRNPC1RAB9APTPN1GSK3B | |
| SCHEMBL204756 | 0.80 | PTPN1 (0.50) | TTRPTPN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6841233 | 0.80 | TTR (0.55) | TTRNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL11835904 | 0.80 | NPC1 (0.51) | TTRNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL11798714 | 0.79 | NPC1 (0.54) | TTRNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL68189 | 0.78 | TTR (0.83) | TTRNPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3953602-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-04-27 | — | — | US | disclosed |