Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 5/20 | 0.47 |
| ▸ | THRA | P10827 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719502 | 0.90 | THRB (0.55) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL11812323 | 0.80 | TSHR (0.54) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL5144090 | 0.80 | TSHR (0.79) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL25426 | 0.80 | TSHR (0.79) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL10604787 | 0.80 | TSHR (0.46) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL15302575 | 0.79 | TDP1 (0.55) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL9580207 | 0.78 | THRB (0.46) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL22554429 | 0.78 | TSHR (0.83) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL22023212 | 0.78 | TSHR (0.83) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL5607699 | 0.78 | TSHR (0.83) | TSHRTDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932321-A | HOMO- AND COPOLYMERS OF HALOPHENYL ACRYLATES | JAPAN SYNTHETIC RUBBER COMPANY LIMITED (JA) | 1976-01-13 | — | — | US | claimed |
| US-3932321-A | HOMO- AND COPOLYMERS OF HALOPHENYL ACRYLATES | JAPAN SYNTHETIC RUBBER COMPANY LIMITED (JA) | 1976-01-13 | — | — | US | disclosed |