Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADH5 | P11766 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11801781 | 1.00 | SRD5A2 (0.43) | SRD5A2ALDH1A1KDM4EL3MBTL1CSNK2A1 | |
| SCHEMBL11801787 | 1.00 | SRD5A2 (0.43) | SRD5A2ALDH1A1KDM4EL3MBTL1CSNK2A1 | |
| SCHEMBL7367792 | 0.82 | MAPT (0.55) | SRD5A2ALDH1A1KDM4EL3MBTL1CSNK2A1 | |
| SCHEMBL11803058 | 0.82 | PTGS1 (0.49) | ALDH1A1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL11803073 | 0.82 | PTGS1 (0.49) | ALDH1A1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL11803068 | 0.82 | PTGS1 (0.49) | ALDH1A1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL11803701 | 0.81 | CYP2A6 (0.46) | KDM4EMAPTSMN1; SMN2CYP2A6 | |
| SCHEMBL11803694 | 0.81 | CYP2A6 (0.46) | KDM4EMAPTSMN1; SMN2CYP2A6 | |
| SCHEMBL11803688 | 0.81 | CYP2A6 (0.46) | KDM4EMAPTSMN1; SMN2CYP2A6 | |
| SCHEMBL9609545 | 0.79 | TSHR (0.53) | SRD5A2KDM4EKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950427-A | ANTIINFLAMMATORY, ANTIPYRETIC | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |