Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803139 | 1.00 | MAOB (0.49) | MAOBMAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11796564 | 0.99 | MAOB (0.50) | MAOBMAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11800862 | 0.95 | MAOB (0.51) | MAOBMAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11799177 | 0.93 | MAOB (0.47) | MAOBMAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11803335 | 0.91 | L3MBTL1 (0.51) | MAOBMAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11797278 | 0.87 | MAPT (0.51) | MAOBMAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11807107 | 0.86 | MAOB (0.52) | MAOBMAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11807128 | 0.86 | MAPT (0.47) | MAOBMAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11805183 | 0.82 | L3MBTL1 (0.52) | MAOBMAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11796833 | 0.82 | L3MBTL1 (0.49) | MAOBMAPTRAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933837-A | 3,4-Methylenedioxyphenoxy-alkyl diketones and keto-esters | STERLING DRUG INC. (US) | 1976-01-20 | — | — | US | claimed |
| US-3933837-A | 3,4-Methylenedioxyphenoxy-alkyl diketones and keto-esters | STERLING DRUG INC. (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933472-A | Substituted alkylaryl ketones and methods of use as herbicides | BUCKMAN LABORATORIES, INC. (US) | 1976-01-20 | — | — | US | disclosed |