Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803547 | 0.89 | EPHX2 (0.43) | KDM4EHTTSIGMAR1GRIN2DGRIN3B | |
| SCHEMBL3580028 | 0.79 | KDM4E (0.44) | KDM4EHTTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL29839703 | 0.76 | GRIN2D (0.50) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6937606 | 0.74 | GRIN2D (0.43) | KDM4EHTTSIGMAR1GRIN2DGRIN3B | |
| SCHEMBL10700984 | 0.74 | GRIN2D (0.52) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28905098 | 0.74 | MAPT (0.40) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11804068 | 0.74 | SMN1; SMN2 (0.46) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL11802220 | 0.73 | KMT2A (0.45) | KDM4ESIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11804075 | 0.73 | EPHX2 (0.50) | EPHX2 | |
| Hydrochloric Acid SCHEMBL1677958 | 0.72 | GRIN2D (0.50) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941885-A | N-ADAMANTANYL AMINO ALKANOIC ACID | SCHERING CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
| US-3941885-A | N-ADAMANTANYL AMINO ALKANOIC ACID | SCHERING CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |