Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CYP26A1 | O43174 | 12/20 | 0.57 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011514 | 0.88 | HPGD (0.73) | HPGDCYP3A4ALDH1A1HSD17B10CYP26A1 | |
| SCHEMBL29489400 | 0.88 | HPGD (0.73) | HPGDCYP3A4ALDH1A1HSD17B10CYP26A1 | |
| SCHEMBL16344079 | 0.84 | ALDH1A1 (0.68) | HPGDCYP3A4ALDH1A1HSD17B10CYP26A1 | |
| SCHEMBL11802401 | 0.84 | CYP26A1 (0.45) | HPGDCYP3A4ALDH1A1HSD17B10CYP26A1 | |
| SCHEMBL19763106 | 0.83 | HPGD (0.66) | HPGDCYP3A4ALDH1A1HSD17B10CYP26A1 | |
| SCHEMBL15505824 | 0.83 | HPGD (0.64) | HPGDCYP3A4ALDH1A1HSD17B10CYP26A1 | |
| SCHEMBL15960970 | 0.83 | HPGD (0.65) | HPGDCYP3A4ALDH1A1HSD17B10CYP26A1 | |
| SCHEMBL10712966 | 0.82 | HPGD (0.56) | HPGDCYP3A4ALDH1A1HSD17B10CYP26A1 | |
| SCHEMBL10781589 | 0.81 | HPGD (0.68) | HPGDCYP3A4ALDH1A1HSD17B10CYP26A1 | |
| SCHEMBL20342387 | 0.79 | CYP2A6 (0.68) | HPGDCYP3A4ALDH1A1HSD17B10CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3944492-A | Lubricant compositions containing N-substituted naphthylamines as antioxidants | UNIROYAL, INC. (US) | 1976-03-16 | — | — | US | claimed |
| US-3944492-A | Lubricant compositions containing N-substituted naphthylamines as antioxidants | UNIROYAL, INC. (US) | 1976-03-16 | — | — | US | disclosed |