SCHEMBL11802449

SCHEMBL11802449

c1ccc(C2CCCCCCCCC(c3ccccc3)/N=N\C(c3ccccc3)CCCCCCCCC(c3ccccc3)/N=N\2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.55
NOS2 P35228 2/20 0.55
SLC18A3 Q16572 2/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
CYP11B2 P19099 1/20 0.41
TAAR1 Q96RJ0 3/20 0.39
MAOA P21397 7/20 0.39
MAOB P27338 7/20 0.39
KDM1A O60341 5/20 0.39
CYP2C19 P33261 4/20 0.39
CYP2B6 P20813 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11802455 1.00 NOS1 (0.55) NOS1NOS2SLC18A3ALDH1A1GAA
SCHEMBL11777702 1.00 NOS1 (0.55) NOS1NOS2SLC18A3ALDH1A1GAA
SCHEMBL10622601 0.93 NOS1 (0.52) NOS1NOS2SLC18A3ALDH1A1GAA
SCHEMBL11292416 0.87 NOS1 (0.45) NOS1NOS2SLC18A3TAAR1MAOA
SCHEMBL6629532 0.80 NOS1 (0.46) NOS1NOS2SLC18A3ALDH1A1GAA
SCHEMBL3173918 0.80 NOS1 (0.50) NOS1NOS2SLC18A3ALDH1A1GAA
SCHEMBL8542775 0.80 NOS1 (0.50) NOS1NOS2SLC18A3ALDH1A1GAA
SCHEMBL186274 0.77 NOS1 (0.52) NOS1NOS2SLC18A3ALDH1A1GAA
SCHEMBL6268220 0.77 MAOB (0.50) NOS1NOS2TAAR1MAOAMAOB
SCHEMBL3115176 0.74 NOS1 (0.48) NOS1NOS2SLC18A3ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3970612-A BULK POLYMERIZATION HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-07-20 US disclosed