Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268178 | 0.84 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15348149 | 0.80 | THRB (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL268440 | 0.79 | THRB (0.66) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL36524 | 0.79 | THRB (1.00) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL268727 | 0.78 | THRB (0.65) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11805475 | 0.78 | THRB (0.55) | THRBTSHRALDH1A1 | |
| SCHEMBL13862895 | 0.78 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL27864626 | 0.78 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL20276173 | 0.77 | THRB (0.59) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8850621 | 0.77 | THRB (0.96) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935342-A | POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-27 | — | — | US | disclosed |