Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CLPP | Q16740 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800225 | 0.82 | CYP1A2 (0.56) | HTTKMT2ATSHRSOS1LMNA | |
| SCHEMBL11810117 | 0.81 | KMT2A (0.50) | HTTKMT2ATSHRSOS1LMNA | |
| SCHEMBL11800105 | 0.77 | HTT (0.47) | HTTKMT2ATSHRSOS1LMNA | |
| SCHEMBL11842852 | 0.76 | TSHR (0.80) | HTTKMT2ATSHRSOS1LMNA | |
| SCHEMBL11846111 | 0.76 | TSHR (0.68) | HTTKMT2ATSHRSOS1LMNA | |
| Hydrochloric Acid SCHEMBL11845788 | 0.75 | TSHR (0.78) | HTTKMT2ATSHRSOS1LMNA | |
| SCHEMBL11066311 | 0.73 | HTT (0.51) | HTTKMT2ATSHRSOS1LMNA | |
| SCHEMBL11800081 | 0.73 | TSHR (0.53) | HTTKMT2ATSHRSOS1LMNA | |
| SCHEMBL11806199 | 0.72 | TSHR (0.69) | HTTKMT2ATSHRLMNACYP1A2 | |
| SCHEMBL11802928 | 0.71 | TSHR (0.59) | HTTKMT2ATSHRSOS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975386-A | PYRIDOPYRIMIDINE-ONE INTERMEDIATES | SANDOZ, INC. (US) | 1976-08-17 | — | — | US | disclosed |