Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | CLPP | Q16740 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842852 | 0.85 | TSHR (0.80) | TSHRHTTKMT2ASOS1LMNA | |
| Hydrochloric Acid SCHEMBL11845788 | 0.84 | TSHR (0.78) | TSHRHTTKMT2ASOS1LMNA | |
| SCHEMBL11847604 | 0.82 | TSHR (0.65) | TSHRHTTKMT2ASOS1TP53 | |
| SCHEMBL11845293 | 0.81 | TSHR (1.00) | TSHRHTTKMT2ASOS1LMNA | |
| SCHEMBL11850001 | 0.79 | TSHR (0.74) | TSHRHTTKMT2ASOS1LMNA | |
| SCHEMBL11843146 | 0.78 | SOS1 (0.74) | TSHRHTTKMT2ASOS1LMNA | |
| SCHEMBL11855278 | 0.77 | TSHR (0.75) | TSHRHTTKMT2ASOS1LMNA | |
| SCHEMBL11810117 | 0.76 | KMT2A (0.50) | TSHRHTTKMT2ASOS1LMNA | |
| SCHEMBL11804124 | 0.76 | HTT (0.49) | TSHRHTTKMT2ASOS1LMNA | |
| SCHEMBL11850097 | 0.75 | TSHR (0.52) | TSHRLMNATP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |