Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574123 | 0.93 | CA1 (0.55) | CA1CA2LMNAHTTMEN1 | |
| SCHEMBL6076034 | 0.93 | CA1 (0.59) | CA1CA2LMNAHTTMEN1 | |
| SCHEMBL8712803 | 0.91 | HTT (0.54) | CA1CA2LMNAHTTMEN1 | |
| SCHEMBL9115251 | 0.90 | LMNA (0.55) | CA1CA2LMNAHTTMEN1 | |
| SCHEMBL11295651 | 0.88 | HTT (0.56) | CA1CA2LMNAHTTMEN1 | |
| SCHEMBL8569762 | 0.88 | LMNA (0.54) | CA1CA2LMNAHTTMEN1 | |
| SCHEMBL8570941 | 0.88 | LMNA (0.54) | CA1CA2LMNAHTTMEN1 | |
| SCHEMBL2935246 | 0.87 | CA1 (0.61) | CA1CA2LMNAHTTMEN1 | |
| SCHEMBL6076944 | 0.84 | KMT2A (0.52) | CA1CA2LMNAHTTMEN1 | |
| SCHEMBL1587515 | 0.84 | LMNA (0.47) | CA1CA2LMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3963765-A | Preparation of derivatives of cholesterol | MAZUR YEHUDA | 1976-06-15 | — | — | US | disclosed |
| US-3956402-A | MICROBIOCIDES | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |