Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.65 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11806441 | 0.84 | ADRB2 (0.71) | ADRB2ADRB1ALDH1A1LMNANPSR1 | |
| SCHEMBL11807190 | 0.83 | ADRB2 (0.56) | ADRB2ADRB1ALDH1A1LMNANPSR1 | |
| SCHEMBL7337495 | 0.82 | ADRB2 (0.72) | ADRB2ADRB1ALDH1A1LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL7348099 | 0.81 | ADRB2 (0.70) | ADRB2ADRB1ALDH1A1LMNANPSR1 | |
| Denopamine SCHEMBL29964546 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1ALDH1A1LMNANPSR1 | |
| Denopamine SCHEMBL4542605 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1ALDH1A1LMNANPSR1 | |
| Denopamine SCHEMBL218641 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1ALDH1A1LMNANPSR1 | |
| Denopamine SCHEMBL218640 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1ALDH1A1LMNANPSR1 | |
| Oxalic Acid SCHEMBL11804094 | 0.79 | ADRB2 (0.59) | ADRB2ADRB1ALDH1A1LMNANPSR1 | |
| SCHEMBL2970029 | 0.79 | STAT3 (0.57) | ADRB2ADRB1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3952021-A | α-(3,4-Dimethoxyphenethylaminomethyl)-3,4 or 3,5-dihydroxybenzylalcohols and salts thereof | TANABE SEIYAKU CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |