Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808705 | 0.86 | KMT2A (0.68) | KMT2AMEN1ALDH1A1HTTALOX12 | |
| SCHEMBL11515272 | 0.83 | KMT2A (0.77) | KMT2AMEN1ALDH1A1HTTALOX12 | |
| SCHEMBL5454958 | 0.83 | KMT2A (1.00) | KMT2AMEN1ALDH1A1HTTALOX12 | |
| SCHEMBL11514074 | 0.81 | KMT2A (0.73) | KMT2AMEN1ALDH1A1HTTALOX12 | |
| SCHEMBL11814225 | 0.81 | KMT2A (0.83) | KMT2AMEN1ALDH1A1HTTALOX12 | |
| SCHEMBL11512166 | 0.80 | KMT2A (0.71) | KMT2AMEN1ALDH1A1HTTALOX12 | |
| SCHEMBL11755573 | 0.79 | KMT2A (0.71) | KMT2AMEN1ALDH1A1HTTALOX12 | |
| SCHEMBL31388347 | 0.79 | KMT2A (0.71) | KMT2AMEN1ALDH1A1HTTALOX12 | |
| SCHEMBL11805665 | 0.78 | KMT2A (0.61) | KMT2AMEN1ALDH1A1HTTALOX12 | |
| SCHEMBL11801503 | 0.77 | KMT2A (0.68) | KMT2AMEN1ALDH1A1HTTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933833-A | ANTIINFLAMMATORY | THE DOW CHEMICAL COMPANY (US) | 1976-01-20 | — | — | US | claimed |
| US-3933833-A | ANTIINFLAMMATORY | THE DOW CHEMICAL COMPANY (US) | 1976-01-20 | — | — | US | disclosed |