Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.46 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814861 | 0.98 | LTB4R (0.55) | LTB4RTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL11768302 | 0.97 | LTB4R (0.57) | LTB4RTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL11772872 | 0.95 | LTB4R (0.49) | LTB4RTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL11816756 | 0.91 | LTB4R (0.52) | LTB4RTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL11485965 | 0.91 | KDM4E (0.45) | LTB4RTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL11775457 | 0.91 | TTR (0.49) | LTB4RTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL11767255 | 0.88 | LTB4R (0.48) | LTB4RTP53TTRACSL1ACSL6 | |
| SCHEMBL11768039 | 0.88 | LTB4R (0.48) | LTB4RTP53TTRACSL1ACSL6 | |
| SCHEMBL11767469 | 0.88 | LTB4R (0.48) | LTB4RALDH1A1ACSL1ACSL6 | |
| SCHEMBL11769089 | 0.88 | LTB4R (0.48) | LTB4RTP53TTRACSL1ACSL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951618-A | Method of use of, and compositions containing, disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-20 | — | — | US | disclosed |