Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.58 |
| ▸ | F3 | P13726 | 1/20 | 0.58 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.58 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82140 | 0.87 | ALDH1A1 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL29993557 | 0.85 | ALDH1A1 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL888775 | 0.85 | ALDH1A1 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL14490189 | 0.83 | ALDH1A1 (0.57) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL27598428 | 0.82 | ALDH1A1 (0.50) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL28782680 | 0.81 | ALDH1A1 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL18204967 | 0.81 | ALDH1A1 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL2585322 | 0.81 | ALDH1A1 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL16313508 | 0.81 | ALDH1A1 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL20966338 | 0.81 | ALDH1A1 (0.55) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969363-A | CARDIOVASCULAR DISORDERS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-07-13 | — | — | US | disclosed |