Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.43 |
| ▸ | MME | P08473 | 8/20 | 0.43 |
| ▸ | CPA1 | P15085 | 8/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898803 | 0.83 | MGAM (0.44) | ACEMMECPA1ACE2TSHR | |
| SCHEMBL14239656 | 0.82 | TSHR (0.50) | TSHRHSD17B10MMP1MGAMGAA | |
| SCHEMBL28718238 | 0.80 | TSHR (0.42) | ACEMMECPA1ACE2TSHR | |
| SCHEMBL7631058 | 0.80 | TSHR (0.44) | TSHRHSD17B10MMP1MGAMGAA | |
| SCHEMBL10329464 | 0.77 | TSHR (0.41) | TSHRHSD17B10MMP1MGAMGAA | |
| SCHEMBL5898819 | 0.76 | — | — | |
| SCHEMBL8499849 | 0.75 | — | — | |
| SCHEMBL5898830 | 0.75 | — | — | |
| SCHEMBL690378 | 0.75 | — | — | |
| SCHEMBL5081302 | 0.74 | TSHR (0.50) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954843-A | ODORANTS, FLAVORANTS | GIVAUDAN CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
| US-3948816-A | ODORANTS AND FLAVORANTS | GIVAUDAN CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |