SCHEMBL10329464

SCHEMBL10329464

COC(=O)CC(S)C(S)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
HSD17B10 Q99714 1/20 0.41
MGAM O43451 2/20 0.36
GAA P10253 2/20 0.36
SI P14410 2/20 0.36
MGAM2 Q2M2H8 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
MMP1 P03956 4/20 0.33
KMT2A Q03164 2/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
TET2 Q6N021 1/20 0.30
CA14 Q9ULX7 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14239656 0.84 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL7631058 0.77 TSHR (0.44) TSHRHSD17B10MGAMGAASI
SCHEMBL8576325 0.77 TSHR (0.44) TSHRHSD17B10MGAMGAASI
SCHEMBL29926745 0.77 TSHR (0.44) TSHRHSD17B10MGAMGAASI
SCHEMBL11809153 0.77 ACE (0.43) TSHRHSD17B10MGAMGAASI
SCHEMBL7640960 0.75 SMN1; SMN2 (0.48) TSHRHSD17B10SMN1; SMN2MMP1KMT2A
SCHEMBL10329462 0.75 SMN1; SMN2 (0.48) TSHRHSD17B10SMN1; SMN2MMP1KMT2A
SCHEMBL7815768 0.75 TSHR (0.43) TSHRHSD17B10MGAMGAASI
SCHEMBL7784843 0.74 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL8499849 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8221965-B2 Antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-07-17 US disclosed
US-8221965-B2 Antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-07-17 US disclosed
US-20100009293-A1 Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2010-01-14 US disclosed
US-20100009293-A1 Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2010-01-14 US disclosed
WO-2010004377-A1 ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-01-14 WO disclosed