Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PDE6D | O43924 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL2694080 | 0.87 | THRB (0.56) | THRBSMN1; SMN2ALDH1A1PDE6DTHRA | |
| SCHEMBL28916 | 0.87 | THRB (0.58) | THRBSMN1; SMN2ALDH1A1TP53CYP3A4 | |
| Hydrogen Peroxide SCHEMBL28479331 | 0.87 | THRB (0.58) | THRBSMN1; SMN2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL29037085 | 0.85 | THRB (0.56) | THRBSMN1; SMN2ALDH1A1TP53CYP3A4 | |
| Potassium SCHEMBL30641492 | 0.85 | THRB (0.56) | THRBSMN1; SMN2ALDH1A1TP53CYP3A4 | |
| Lithium SCHEMBL30641493 | 0.85 | THRB (0.56) | THRBSMN1; SMN2ALDH1A1TP53CYP3A4 | |
| SCHEMBL11576296 | 0.85 | THRB (0.56) | THRBSMN1; SMN2ALDH1A1TP53CYP3A4 | |
| SCHEMBL30350971 | 0.85 | THRB (0.56) | THRBSMN1; SMN2ALDH1A1TP53CYP3A4 | |
| SCHEMBL10479978 | 0.85 | THRB (0.56) | THRBSMN1; SMN2ALDH1A1TP53CYP3A4 | |
| SCHEMBL28429842 | 0.85 | THRB (0.56) | THRBSMN1; SMN2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935342-A | POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-27 | — | — | US | disclosed |