Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.64 |
| ▸ | AR | P10275 | 6/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4210007 | 0.81 | PGR (0.63) | PGRARNR3C2CYP19A1NR3C1 | |
| Gestadienol SCHEMBL931512 | 0.80 | AR (0.65) | PGRARNR3C2NR3C1PDE4D | |
| SCHEMBL13809834 | 0.80 | AR (0.58) | PGRARNR3C2CYP19A1 | |
| SCHEMBL1656805 | 0.80 | AR (0.58) | PGRARNR3C2CYP19A1 | |
| SCHEMBL12949430 | 0.79 | PGR (0.67) | PGRARNR3C2NR3C1CYP3A4 | |
| SCHEMBL2833264 | 0.79 | PGR (0.62) | PGRARNR3C2NR3C1CYP3A4 | |
| SCHEMBL12949722 | 0.79 | PGR (0.67) | PGRARNR3C2NR3C1CYP3A4 | |
| SCHEMBL13013797 | 0.78 | AR (1.00) | PGRARNR3C2 | |
| SCHEMBL12924023 | 0.78 | AR (1.00) | PGRARNR3C2 | |
| SCHEMBL13013564 | 0.78 | AR (1.00) | PGRARNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3968132-A | (17R)-Spiro-[androstane-17,1'-cyclobutan]-2'-ones, methods for their manufacture and intermediates useful therein | SCHERING CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |