Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812777 | 0.91 | CYP4F2 (0.47) | CYP4F2CYP4A11CYP1A2MAPTCYP2C19 | |
| SCHEMBL11834926 | 0.89 | CCNC (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11812368 | 0.85 | CYP4F2 (0.48) | CYP4F2CYP4A11CYP1A2MAPTCYP2C19 | |
| SCHEMBL11817197 | 0.83 | CYP4F2 (0.40) | CYP4F2CYP4A11CYP1A2MAPTCYP2C19 | |
| SCHEMBL11817553 | 0.79 | CCNC (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11810268 | 0.77 | CYP1A2 (0.44) | CYP1A2MAPTCYP2C19RECQLPOLB | |
| SCHEMBL11807967 | 0.73 | CCNC (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11816255 | 0.72 | CCNC (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5741519 | 0.72 | CYP1A2 (0.55) | CYP1A2MAPTCYP2C19RECQLPOLB | |
| SCHEMBL13921687 | 0.72 | CYP4F2 (0.61) | CYP4F2CYP4A11ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994908-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIRHEUMATIC | SHIONOGI & CO., LTD. (JA) | 1976-11-30 | — | — | US | disclosed |
| US-3953512-A | Process for manufacturing 2-aminobutanol | POLSKA AKADEMIA NAUK INSTYTUT CHEMII ORGANICZNEJ (PO) | 1976-04-27 | — | — | US | disclosed |
| US-3940403-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1976-02-24 | — | — | US | disclosed |