Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | GRN | P28799 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817197 | 0.90 | CYP4F2 (0.40) | ALDH1A1 | |
| SCHEMBL11817553 | 0.85 | CCNC (0.43) | CCNCCDK8NPC1ALDH1A1RAB9A | |
| SCHEMBL11834926 | 0.83 | CCNC (0.42) | CCNCCDK8NPC1ALDH1A1RAB9A | |
| SCHEMBL11807967 | 0.79 | CCNC (0.44) | CCNCCDK8NPC1ALDH1A1RAB9A | |
| SCHEMBL11818838 | 0.78 | CCNC (0.42) | CCNCCDK8NPC1ALDH1A1RAB9A | |
| SCHEMBL11816241 | 0.77 | ACACB (0.37) | NPC1ALDH1A1RAB9AACACBMAPK8 | |
| SCHEMBL11818833 | 0.76 | CCNC (0.42) | CCNCCDK8NPC1ALDH1A1RAB9A | |
| SCHEMBL11812777 | 0.74 | CYP4F2 (0.47) | ALDH1A1MEN1CASP3KMT2A | |
| SCHEMBL11817181 | 0.73 | MAPT (0.40) | NPC1ALDH1A1RAB9AACACBMAPK8 | |
| SCHEMBL11810282 | 0.72 | CYP4F2 (0.45) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994908-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIRHEUMATIC | SHIONOGI & CO., LTD. (JA) | 1976-11-30 | — | — | US | disclosed |
| US-3940403-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1976-02-24 | — | — | US | disclosed |