Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1622230 | 0.81 | MAPT (0.48) | GAAMAPTAGTR1KDM4E | |
| SCHEMBL11810763 | 0.80 | KDM4E (0.35) | GAAMAPTESR1ESR2HDAC6 | |
| SCHEMBL3627201 | 0.73 | ESR1 (0.46) | GAAMAPTESR1ESR2HDAC6 | |
| SCHEMBL13766429 | 0.69 | APP (0.62) | MAPTESR1ESR2SMN1; SMN2IKBKB | |
| SCHEMBL18724120 | 0.68 | PDE3B (0.40) | GAAMAPTAGTR1 | |
| SCHEMBL10332042 | 0.68 | GRIN2B (0.38) | MAPTFDPSKDM4EDHODH | |
| SCHEMBL12603805 | 0.68 | AHR (0.61) | — | |
| SCHEMBL22296375 | 0.67 | BCL2 (0.50) | GAAMAPTAGTR1ESR2KDM4E | |
| SCHEMBL1755262 | 0.67 | MAPT (0.49) | GAAMAPTAGTR1KDM4E | |
| SCHEMBL12259927 | 0.67 | CYP3A4 (0.56) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3993645-A | Stilbene optical brighteners and compositions brightened therewith | STERLING DRUG INC. (US) | 1976-11-23 | — | — | US | disclosed |
| US-3974144-A | BENZOFURAN, BENZOTHIOPHENE, NAPHTHOFURAN, OPTICAL BRIGHTENER | STERLING DRUG INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3932301-A | NYLON, POLYESTERS | STERLING DRUG INC. (US) | 1976-01-13 | — | — | US | disclosed |