Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812235 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ALOX15MAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL10540928 | 0.77 | ALDH1A1 (0.64) | ALDH1A1ALOX15MAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL10537870 | 0.77 | ALDH1A1 (0.64) | ALDH1A1ALOX15MAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL11801399 | 0.76 | ALDH1A1 (0.36) | ALDH1A1ALOX15GAA | |
| SCHEMBL11801404 | 0.76 | ALDH1A1 (0.36) | ALDH1A1ALOX15GAA | |
| SCHEMBL11799708 | 0.74 | ALDH1A1 (0.42) | ALDH1A1ALOX15MAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL11799706 | 0.74 | ALDH1A1 (0.42) | ALDH1A1ALOX15MAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL11802415 | 0.69 | ALDH1A1 (0.38) | ALDH1A1ALOX15MAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL11802419 | 0.69 | ALDH1A1 (0.38) | ALDH1A1ALOX15MAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL11804789 | 0.67 | ALDH1A1 (0.52) | ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948994-A | Oxo-and hydroxy-substituted stilbenes | PHILLIPS PETROLEUM COMPANY (US) | 1976-04-06 | — | — | US | disclosed |