Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794925 | 0.91 | ALDH1A1 (0.51) | TP53MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL11820145 | 0.86 | MEN1 (0.46) | TP53MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL11822223 | 0.82 | MEN1 (0.46) | TP53MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL11821792 | 0.82 | MAPT (0.48) | TP53MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL13722496 | 0.81 | MEN1 (0.60) | MEN1KMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL6790960 | 0.81 | KMT2A (0.58) | MEN1KMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL11814079 | 0.80 | TP53 (0.64) | TP53MAPTALDH1A1CES2CES1 | |
| Dinitrophenylene SCHEMBL28982637 | 0.79 | TP53 (0.82) | TP53MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL11816911 | 0.78 | CA12 (0.47) | MEN1KMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL8671668 | 0.78 | MEN1 (0.60) | MEN1KMT2AMAPTCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |