Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911140 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL26042865 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL16272268 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL23885286 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL3330500 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL3330505 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL15103671 | 0.76 | MAPT (0.41) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL15057387 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL8568179 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL30258234 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HTTRAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937831-A | CHLOROMETHYL NITROPYRIDINES AS ANTIMICROBIALS | THE DOW CHEMICAL COMPANY (US) | 1976-02-10 | — | — | US | disclosed |