Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816758 | 0.83 | CISD1 (0.77) | CISD1MEN1KMT2AAPPCA12 | |
| SCHEMBL5926462 | 0.78 | MEN1 (0.63) | MEN1KMT2AGAACD38KDM4E | |
| SCHEMBL11820603 | 0.76 | APP (0.80) | CISD1APPCA12CA1CA2 | |
| SCHEMBL15444359 | 0.76 | MEN1 (0.56) | MEN1KMT2AGAACD38KDM4E | |
| SCHEMBL11823275 | 0.73 | CISD1 (0.57) | CISD1MEN1KMT2AAPPCA12 | |
| SCHEMBL11817302 | 0.73 | APP (0.55) | CISD1MEN1KMT2AAPPCA12 | |
| SCHEMBL11825299 | 0.72 | CISD1 (0.79) | CISD1MEN1KMT2AAPPCA12 | |
| SCHEMBL4658771 | 0.71 | HPGD (0.48) | MEN1KMT2AALDH1A1CD38TSHR | |
| SCHEMBL1716052 | 0.71 | CISD1 (1.00) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL4204375 | 0.70 | MAPT (0.71) | MEN1KMT2AALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953476-A | DIURETICS | MERCK & CO., INC. (US) | 1976-04-27 | — | — | US | disclosed |