Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 8/20 | 0.77 |
| ▸ | CA12 | O43570 | 6/20 | 0.62 |
| ▸ | CA1 | P00915 | 6/20 | 0.62 |
| ▸ | CA2 | P00918 | 6/20 | 0.62 |
| ▸ | CA6 | P23280 | 6/20 | 0.62 |
| ▸ | CA7 | P43166 | 6/20 | 0.62 |
| ▸ | CA9 | Q16790 | 6/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.62 |
| ▸ | CA3 | P07451 | 5/20 | 0.62 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.62 |
| ▸ | CA5A | P35218 | 5/20 | 0.62 |
| ▸ | APP | P05067 | 4/20 | 0.56 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716052 | 0.87 | CISD1 (1.00) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL11823275 | 0.84 | CISD1 (0.57) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL11815670 | 0.83 | CISD1 (0.55) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL11817302 | 0.82 | APP (0.55) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL11820603 | 0.82 | APP (0.80) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL6902427 | 0.81 | CISD1 (0.54) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL12418658 | 0.80 | CISD1 (0.81) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL13545223 | 0.79 | CISD1 (0.80) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL18425099 | 0.78 | CISD1 (0.78) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL13543235 | 0.78 | CISD1 (0.78) | CISD1CA12CA1CA2CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953476-A | DIURETICS | MERCK & CO., INC. (US) | 1976-04-27 | — | — | US | disclosed |