Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ATP4A | P20648 | 8/20 | 0.54 |
| ▸ | ATP4B | P51164 | 8/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369155 | 0.84 | KMT2A (0.72) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5022950 | 0.84 | KMT2A (0.72) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11817262 | 0.82 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9972400 | 0.77 | SRC (0.53) | NPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL1822612 | 0.77 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11878533 | 0.77 | CYP2D6 (0.65) | MEN1KMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL5027312 | 0.76 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11818548 | 0.76 | LTA4H (0.67) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11820987 | 0.75 | LTA4H (0.67) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5023516 | 0.75 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957999-A | ADMINISTERING | THE BOOTS COMPANY (EN) | 1976-05-18 | — | — | US | disclosed |