SCHEMBL11816865

SCHEMBL11816865

Cc1ccc(N(c2ccccc2)c2ccccc2)c(C)c1N(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
CYP1A2 P05177 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NR3C1 P04150 1/20 0.33
APP P05067 1/20 0.32
TSHR P16473 3/20 0.31
FAAH O00519 1/20 0.31
PHGDH O43175 1/20 0.31
MGLL Q99685 1/20 0.31
GLA P06280 1/20 0.31
MEN1 O00255 3/20 0.30
KMT2A Q03164 3/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18209352 0.88 ALDH1A1 (0.37) ALDH1A1CYP1A2TDP1KDM4ECYP3A4
SCHEMBL25977677 0.85 HDAC6 (0.32) ALDH1A1CYP1A2TDP1KDM4ECYP3A4
SCHEMBL9468575 0.85 ALDH1A1 (0.38) ALDH1A1CYP1A2TDP1KDM4ECYP3A4
SCHEMBL27714929 0.82 CYP1A2 (0.33) ALDH1A1CYP1A2TDP1KDM4ECYP3A4
SCHEMBL5245029 0.79 ALDH1A1 (0.37) ALDH1A1CYP1A2TDP1KDM4ECYP3A4
SCHEMBL18872978 0.79 ALDH1A1 (0.39) ALDH1A1CYP1A2TDP1KDM4ECYP3A4
SCHEMBL7883806 0.76 TSHR (0.43) ALDH1A1CYP1A2TDP1KDM4ECYP3A4
SCHEMBL13292382 0.76 TSHR (0.35) ALDH1A1CYP1A2TDP1KDM4ECYP3A4
SCHEMBL29354487 0.75 ALDH1A1 (0.44) ALDH1A1CYP1A2TDP1KDM4ECYP3A4
SCHEMBL313707 0.75 ALDH1A1 (0.44) ALDH1A1CYP1A2TDP1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3932182-A An organic photoconductive composition comprising an organic photoconductive compound and a sensitizing compound having an active methylene group MITSUBISHI PAPER MILLS, LTD. (JA) 1976-01-13 US disclosed