Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | XBP1 | P17861 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816970 | 1.00 | MAPT (0.61) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL11290392 | 0.83 | MEN1 (0.54) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL11290388 | 0.83 | MEN1 (0.54) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL8283668 | 0.83 | CYP2C9 (0.59) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL8346191 | 0.82 | CYP1A2 (0.62) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL8999995 | 0.82 | CYP1A2 (0.62) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL14012043 | 0.80 | MAPT (0.69) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL16807421 | 0.80 | MAPT (0.69) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL13044103 | 0.80 | MEN1 (0.50) | MAPTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL22462351 | 0.77 | F10 (0.68) | MAPTALDH1A1NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957762-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-05-18 | — | — | US | disclosed |