Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256459 | 0.89 | GRIN2B (0.51) | JAK1ALDH1A1L3MBTL1KMT2AGLA | |
| Ammonia Solution, Strong SCHEMBL16269263 | 0.87 | GRIN2B (0.50) | JAK1ALDH1A1L3MBTL1KMT2AGLA | |
| SCHEMBL1701911 | 0.78 | GRIN2B (0.59) | KMT2ARAB9AGRIN2B | |
| SCHEMBL25007080 | 0.76 | JAK1 (0.47) | JAK1ALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL16366457 | 0.76 | JAK1 (0.47) | JAK1ALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL9252404 | 0.72 | ALDH1A1 (0.68) | ALDH1A1POLBGLAKDM4ECXCR4 | |
| SCHEMBL11509945 | 0.72 | ALDH1A1 (0.68) | ALDH1A1POLBGLAKDM4ECXCR4 | |
| SCHEMBL25188602 | 0.71 | HSD17B10 (0.52) | KMT2ARAB9AGRIN2B | |
| SCHEMBL25007083 | 0.71 | JAK1 (0.41) | JAK1ALDH1A1L3MBTL1GLASMN1; SMN2 | |
| SCHEMBL11200026 | 0.70 | SMN1; SMN2 (0.52) | ALDH1A1L3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3946038-A | CHAIN EXTENDERS FOR POLYURETHANES | UNIROYAL, INC. (US) | 1976-03-23 | — | — | US | claimed |
| US-3946038-A | CHAIN EXTENDERS FOR POLYURETHANES | UNIROYAL, INC. (US) | 1976-03-23 | — | — | US | disclosed |