Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784646 | 0.84 | NR1I2 (0.47) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11784648 | 0.81 | MAPT (0.46) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL3522604 | 0.80 | NR1I2 (0.62) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL3519615 | 0.77 | CASR (0.41) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL3521859 | 0.77 | CASR (0.53) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL3521741 | 0.76 | CASR (0.50) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11783244 | 0.75 | NR1I2 (0.58) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11087025 | 0.74 | CASR (0.51) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL3520129 | 0.74 | CASR (0.54) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL3525704 | 0.74 | NR1I2 (0.48) | NR1I2EGFRADRA2AADORA3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3997564-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1976-12-14 | — | — | US | disclosed |
| US-3978086-A | INTERMEDIATES FOR 2-AMINO-4,5-METHYLENEDIOXYBENZOPHENONIMINES | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |