Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 5/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871992 | 0.89 | SMN1; SMN2 (0.45) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3522604 | 0.84 | NR1I2 (0.62) | PDE4DNR1I2EGFRADRA2AADORA3 | |
| SCHEMBL11410850 | 0.83 | NR1I2 (0.48) | MAPTPDE4DNR1I2EGFRADRA2A | |
| SCHEMBL3521741 | 0.82 | CASR (0.50) | PDE4DNR1I2EGFRADRA2AADORA3 | |
| SCHEMBL11789237 | 0.82 | CASR (0.61) | MAPTNPC1RAB9APDE4DNR1I2 | |
| SCHEMBL11817686 | 0.81 | NR1I2 (0.41) | MAPTALDH1A1PDE4DNR1I2EGFR | |
| SCHEMBL3521859 | 0.80 | CASR (0.53) | PDE4DNR1I2EGFRADRA2AADORA3 | |
| SCHEMBL3525704 | 0.79 | NR1I2 (0.48) | MAPTNPC1RAB9APDE4DNR1I2 | |
| SCHEMBL3522108 | 0.79 | CASR (0.47) | SMN1; SMN2NPC1RAB9APDE4DNR1I2 | |
| SCHEMBL3524289 | 0.79 | CASR (0.47) | SMN1; SMN2NPC1RAB9APDE4DNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3997564-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1976-12-14 | — | — | US | disclosed |
| US-3978086-A | INTERMEDIATES FOR 2-AMINO-4,5-METHYLENEDIOXYBENZOPHENONIMINES | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |