Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816576 | 0.91 | MAPK1 (0.44) | CSNK1DDYRK1AMEN1KMT2AMAPK1 | |
| SCHEMBL11816190 | 0.91 | MAPK1 (0.44) | CSNK1DDYRK1AMEN1KMT2AMAPK1 | |
| SCHEMBL11819779 | 0.91 | MAPK1 (0.44) | CSNK1DDYRK1AMEN1KMT2AMAPK1 | |
| SCHEMBL11819697 | 0.90 | MAPK1 (0.45) | CSNK1DDYRK1AMEN1KMT2AMAPK1 | |
| SCHEMBL11825260 | 0.87 | ACMSD (0.44) | CSNK1DDYRK1AMEN1KMT2AMAPK1 | |
| SCHEMBL11822989 | 0.85 | MEN1 (0.44) | CSNK1DDYRK1AMEN1KMT2AMAPK1 | |
| SCHEMBL11825265 | 0.85 | MEN1 (0.44) | CSNK1DDYRK1AMEN1KMT2AMAPK1 | |
| SCHEMBL11823043 | 0.83 | ACMSD (0.45) | MEN1KMT2AACMSDALDH1A1KDM4E | |
| SCHEMBL11814299 | 0.82 | ACMSD (0.56) | KMT2AACMSDKDM4EHTTTDP1 | |
| SCHEMBL11813502 | 0.81 | MEN1 (0.48) | CSNK1DDYRK1AMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |