Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.57 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27415734 | 0.84 | TDP1 (0.67) | TDP1POLBNCOA1NCOA3ALDH1A1 | |
| SCHEMBL9836130 | 0.81 | TDP1 (0.62) | TDP1POLBNCOA1NCOA3ALDH1A1 | |
| SCHEMBL27932601 | 0.81 | TDP1 (0.62) | TDP1POLBNCOA1NCOA3ALDH1A1 | |
| SCHEMBL2379102 | 0.81 | TDP1 (0.62) | TDP1POLBNCOA1NCOA3ALDH1A1 | |
| SCHEMBL6595618 | 0.81 | TDP1 (0.62) | TDP1POLBNCOA1NCOA3ALDH1A1 | |
| SCHEMBL10549357 | 0.81 | TDP1 (0.62) | TDP1POLBNCOA1NCOA3ALDH1A1 | |
| SCHEMBL619830 | 0.81 | TDP1 (0.62) | TDP1POLBNCOA1NCOA3ALDH1A1 | |
| SCHEMBL13459551 | 0.81 | PLAU (0.44) | TDP1POLBNCOA1NCOA3ALDH1A1 | |
| SCHEMBL29475175 | 0.80 | TDP1 (1.00) | TDP1POLBNCOA1NCOA3ALDH1A1 | |
| SCHEMBL57166 | 0.80 | TDP1 (1.00) | TDP1POLBNCOA1NCOA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3930837-A | 3-CHLORO-5-ACETAMIDAISOQUINOLINE AS A HERBICIDE | ICI AUSTRALIA LIMITED (AU) | 1976-01-06 | — | — | US | disclosed |