Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CHAT | P28329 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821979 | 1.00 | MAPT (0.61) | MAPTLMNACAPN1CTSLCTSB | |
| SCHEMBL7915398 | 0.86 | MAPT (0.63) | MAPTLMNACAPN1CTSLCTSB | |
| SCHEMBL7915395 | 0.86 | MAPT (0.63) | MAPTLMNACAPN1CTSLCTSB | |
| SCHEMBL31618160 | 0.83 | MAPT (0.59) | MAPTLMNACAPN1CTSLCTSB | |
| SCHEMBL2604952 | 0.83 | MAPT (0.79) | MAPTLMNACAPN1CTSLCTSB | |
| SCHEMBL2604932 | 0.81 | LMNA (0.77) | MAPTLMNACAPN1CTSLCTSB | |
| SCHEMBL11670549 | 0.80 | MAPT (0.60) | MAPTLMNACAPN1CTSLCTSB | |
| SCHEMBL11671491 | 0.80 | MAPT (0.60) | MAPTLMNACAPN1CTSLCTSB | |
| SCHEMBL10969530 | 0.80 | MAPT (0.56) | MAPTLMNACAPN1CTSLCTSB | |
| SCHEMBL10969555 | 0.80 | MAPT (0.56) | MAPTLMNACAPN1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985896-A | Benzophenalenofurans | SMITHKLINE CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |