Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819344 | 1.00 | ACMSD (0.56) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL11816217 | 1.00 | ACMSD (0.56) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL11815948 | 0.99 | ACMSD (0.55) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL11814299 | 0.90 | ACMSD (0.56) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL11825260 | 0.88 | ACMSD (0.44) | ACMSDKMT2AL3MBTL1EGLN1 | |
| SCHEMBL11813461 | 0.86 | ACMSD (0.51) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL11816576 | 0.82 | MAPK1 (0.44) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL11816190 | 0.82 | MAPK1 (0.44) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL11819779 | 0.82 | MAPK1 (0.44) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL11819697 | 0.81 | MAPK1 (0.45) | KDM4EKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |