Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818015 | 0.84 | KDM4E (0.46) | NPSR1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL6202289 | 0.83 | DPP4 (0.60) | NPSR1DPP4MAPTGAATHRB | |
| SCHEMBL28319922 | 0.80 | DPP4 (0.61) | NPSR1ALDH1A1DPP4MAPTGAA | |
| SCHEMBL11816190 | 0.80 | MAPK1 (0.44) | NPSR1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL11818762 | 0.80 | CSNK1D (0.43) | NPSR1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL11819779 | 0.80 | MAPK1 (0.44) | NPSR1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL11816576 | 0.80 | MAPK1 (0.44) | NPSR1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL2725474 | 0.79 | MAPT (0.60) | NPSR1KDM4EALDH1A1DPP4MAPT | |
| SCHEMBL4651297 | 0.79 | DPP4 (0.52) | NPSR1KDM4EALDH1A1DPP4MAPT | |
| SCHEMBL11819697 | 0.78 | MAPK1 (0.45) | NPSR1KDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |