Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826212 | 0.91 | CYP1A1 (0.50) | CYP1A1CYP1A2CYP1B1KDM4ECDC25B | |
| SCHEMBL11823673 | 0.84 | AURKA (0.52) | KDM4ELMNACDC25BMEN1KMT2A | |
| SCHEMBL11825432 | 0.84 | AURKA (0.49) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL11830081 | 0.84 | AURKA (0.52) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL11834181 | 0.84 | CDC25B (0.47) | KDM4ELMNACDC25BMEN1KMT2A | |
| SCHEMBL11825676 | 0.84 | LMNA (0.50) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL824364 | 0.83 | CDC25B (0.54) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL11835098 | 0.80 | PLA2G10 (0.47) | L3MBTL1CDC25BMEN1KMT2ANPC1 | |
| SCHEMBL11822310 | 0.76 | AURKA (0.49) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL11836690 | 0.76 | AURKA (0.49) | CYP1A1CYP1A2CYP1B1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000275-A | BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |