Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678015 | 0.86 | HTT (0.48) | HTTHRH3SRD5A2PTGS2CXCL8 | |
| SCHEMBL11811925 | 0.86 | TSHR (0.45) | HTTHRH3SRD5A2PTGS2CXCL8 | |
| SCHEMBL11814670 | 0.85 | HTT (0.47) | HTTHRH3SRD5A2PTGS2CXCL8 | |
| SCHEMBL11813514 | 0.81 | HRH3 (0.46) | HTTHRH3CXCL8 | |
| SCHEMBL7678249 | 0.79 | PTGS2 (0.44) | HTTHRH3PTGS2CXCL8AKR1B1 | |
| SCHEMBL7674823 | 0.77 | HTT (0.44) | HTTHRH3SRD5A2PTGS2CXCL8 | |
| SCHEMBL10945105 | 0.75 | SRD5A2 (0.55) | HTTHRH3SRD5A2PTGS2CXCL8 | |
| SCHEMBL7676873 | 0.74 | HTT (0.44) | HTTHRH3SRD5A2PTGS2CXCL8 | |
| SCHEMBL15641391 | 0.73 | PTGS1 (0.56) | SRD5A2PTGS2CXCL8AKR1B1PTGS1 | |
| SCHEMBL15641390 | 0.73 | PTGS1 (0.56) | SRD5A2PTGS2CXCL8AKR1B1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3952012-A | MULTISTAGE | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-04-20 | — | — | US | disclosed |