Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.53 |
| ▸ | USP5 | P45974 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828647 | 0.84 | FFAR1 (0.60) | FFAR1CYP2C9CYP2D6POLBGABBR2 | |
| SCHEMBL11829613 | 0.81 | FFAR1 (0.47) | FFAR1SMN1; SMN2 | |
| SCHEMBL11837418 | 0.79 | POLB (0.49) | FFAR1CYP2D6POLBSMN1; SMN2NPC1 | |
| SCHEMBL11828611 | 0.78 | MME (0.47) | FFAR1 | |
| SCHEMBL11332403 | 0.78 | FFAR1 (0.62) | FFAR1USP5CYP2C9CYP2D6HIF1A | |
| SCHEMBL11827192 | 0.76 | NPC1 (0.46) | FFAR1POLBSMN1; SMN2NPC1KDM4E | |
| SCHEMBL11827910 | 0.76 | FFAR1 (0.50) | FFAR1HIF1ASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL11835125 | 0.75 | FFAR1 (0.47) | FFAR1CYP2C9HIF1ALMNADRD3 | |
| SCHEMBL11827794 | 0.75 | ALDH1A1 (0.43) | FFAR1MAPK1ALDH1A1 | |
| SCHEMBL6965546 | 0.74 | FFAR1 (0.50) | FFAR1USP5CYP2C9CYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |