Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833636 | 0.83 | PTGDR2 (0.40) | PTGDR2PTGDRPTGER2NSD2NSD1 | |
| SCHEMBL7322430 | 0.81 | PTGDR2 (0.45) | PTGDR2PTGDRPTGER2S1PR1NSD2 | |
| SCHEMBL11825598 | 0.81 | PTGDR2 (0.45) | PTGDR2PTGDRPTGER2S1PR1NSD2 | |
| SCHEMBL11835952 | 0.81 | MITF (0.41) | S1PR1S1PR3 | |
| SCHEMBL11794346 | 0.80 | PTGDR2 (0.42) | PTGDR2PTGDRPTGER2NSD2NSD1 | |
| SCHEMBL11852757 | 0.80 | PTGDR2 (0.44) | PTGDR2PTGDRPTGER2S1PR1NSD2 | |
| SCHEMBL11848738 | 0.77 | PTGDR2 (0.42) | PTGDR2PTGDRPTGER2S1PR1NSD2 | |
| SCHEMBL11567592 | 0.77 | PTGDR2 (0.45) | PTGDR2PTGDRPTGER2S1PR1NSD2 | |
| Hydrochloric Acid SCHEMBL11844291 | 0.76 | PTGDR2 (0.41) | PTGDR2PTGDRPTGER2S1PR1NSD2 | |
| SCHEMBL11700408 | 0.75 | PTGDR2 (0.43) | PTGDR2PTGDRPTGER2NSD2NSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |