Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11827472 | 0.84 | TBXA2R (0.44) | TSHRTBXA2RHMGCRCHRM1ADRA1A | |
| SCHEMBL11830423 | 0.81 | MME (0.44) | TBXA2RHMGCRCHRM1ADRA1ACYP2C19 | |
| SCHEMBL17590423 | 0.80 | TBXA2R (0.54) | MIFTSHRSLC6A4SLC6A2HTR2A | |
| SCHEMBL11830642 | 0.79 | CYP2C9 (0.46) | HTR2ATBXA2RHMGCRCHRM1ADRA1A | |
| SCHEMBL11279619 | 0.78 | PTGES2 (0.53) | TSHRSLC6A4SLC6A2HTR2AHRH1 | |
| SCHEMBL28100624 | 0.77 | SLC6A4 (0.56) | MIFTSHRSLC6A4SLC6A2HTR2A | |
| SCHEMBL8480665 | 0.76 | SLC13A5 (0.50) | MIFTSHRTBXA2RFFAR1SLC13A5 | |
| SCHEMBL11830242 | 0.75 | ALDH1A1 (0.43) | TSHRSLC6A2TBXA2RHMGCRCHRM1 | |
| SCHEMBL11830040 | 0.74 | CSNK2A1 (0.50) | TBXA2RHMGCRCHRM1ADRA1ACYP2C19 | |
| SCHEMBL27666403 | 0.73 | SLC6A4 (0.55) | TSHRSLC6A4SLC6A2HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |