Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
| ▸ | TST | Q16762 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718780 | 0.74 | MEN1 (0.70) | CDK1CCNB1KDM4EMEN1MAPT | |
| SCHEMBL29687268 | 0.73 | CDK1 (0.57) | CDK1CCNB1PDE5AKDM4EMEN1 | |
| SCHEMBL28486812 | 0.73 | CDK1 (0.57) | CDK1CCNB1PDE5AKDM4EMEN1 | |
| SCHEMBL30047574 | 0.69 | ALOX5 (0.62) | KDM4EMEN1MAPTKMT2ASLCO2B1 | |
| SCHEMBL30494621 | 0.68 | MEN1 (0.64) | CDK1CCNB1PDE5AKDM4EMEN1 | |
| SCHEMBL29962900 | 0.68 | MEN1 (0.64) | CDK1CCNB1PDE5AKDM4EMEN1 | |
| SCHEMBL3807701 | 0.67 | CYP1A2 (0.71) | CDK1CCNB1KDM4EMEN1MAPT | |
| SCHEMBL30434092 | 0.67 | KDM4E (0.71) | CDK1CCNB1PDE5AKDM4EMEN1 | |
| SCHEMBL31250385 | 0.67 | KDM4E (0.56) | CDK1CCNB1PDE5AKDM4EMEN1 | |
| SCHEMBL3718774 | 0.67 | MEN1 (0.71) | CDK1CCNB1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424541-A2 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | Limerick BioPharma, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |