Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 6/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873420 | 0.72 | ALDH1A1 (0.47) | DRD1ALDH1A1MAPTMAPK1TP53 | |
| SCHEMBL9851308 | 0.72 | ALDH1A1 (0.47) | DRD1ALDH1A1MAPTMAPK1TP53 | |
| SCHEMBL29858101 | 0.72 | ALDH1A1 (0.47) | DRD1ALDH1A1MAPTMAPK1TP53 | |
| SCHEMBL13302986 | 0.72 | ALDH1A1 (0.47) | DRD1ALDH1A1MAPTMAPK1TP53 | |
| SCHEMBL19888926 | 0.71 | CYP2D6 (0.46) | OPRM1DRD1DRD2DRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17670966 | 0.71 | MAPT (0.50) | ALDH1A1MAPTMAPK1CYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL38652726 | 0.71 | MAPT (0.50) | ALDH1A1MAPTMAPK1CYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL17671007 | 0.71 | MAPT (0.50) | ALDH1A1MAPTMAPK1CYP2D6KDM4E | |
| Bromide SCHEMBL11726490 | 0.70 | CYP2D6 (0.45) | OPRM1DRD1DRD2DRD4ALDH1A1 | |
| SCHEMBL27360801 | 0.69 | PRCP (0.56) | DRD1DRD2DRD4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976634-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1976-08-24 | — | — | US | claimed |
| US-3976634-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1976-08-24 | — | — | US | disclosed |