Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 9/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834463 | 0.88 | CA1 (0.53) | CA1CA2CA9CA12EGFR | |
| SCHEMBL11833061 | 0.85 | CA1 (0.52) | CA1CA2CA9CA12EGFR | |
| SCHEMBL2555263 | 0.82 | CA1 (0.78) | CA1CA2CA9CA12EGFR | |
| SCHEMBL9232639 | 0.76 | CA1 (0.68) | CA1CA2CA9CA12EGFR | |
| SCHEMBL9232630 | 0.73 | CA1 (0.67) | CA1CA2CA9CA12EGFR | |
| SCHEMBL11868510 | 0.72 | CA1 (0.50) | CA1CA2CA9CA12EGFR | |
| SCHEMBL11868504 | 0.72 | CA1 (0.50) | CA1CA2CA9CA12EGFR | |
| SCHEMBL15325008 | 0.71 | CA1 (1.00) | CA1CA2CA9CA12EGFR | |
| SCHEMBL9232636 | 0.70 | CA1 (0.70) | CA1CA2CA9CA12EGFR | |
| SCHEMBL11824972 | 0.70 | EGFR (0.58) | EGFRERBB2GLASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962274-A | 1-AZIDOALKYLIMIDAZOLES | G. D. SEARLE & CO. (US) | 1976-06-08 | — | — | US | disclosed |